Cell cycle-dependent gene networks relevant to cancer
نویسندگان
چکیده
منابع مشابه
Cell-cycle-dependent regulation of erythropoietin receptor gene.
To understand the regulatory mechanism of erythropoietin (EPO) receptor (EPOR) gene expression, the effect of EPO on the steady-state level of EPOR mRNA was examined using the human EPO-dependent cell line UT-7 as a model system. We found that the treatment of UT-7 cells with EPO resulted in a transient decrease of the EPOR mRNA level. This transient downregulation was also induced by stimulati...
متن کاملCell Cycle Gene Networks Are Associated with Melanoma Prognosis
BACKGROUND Our understanding of the molecular pathways that underlie melanoma remains incomplete. Although several published microarray studies of clinical melanomas have provided valuable information, we found only limited concordance between these studies. Therefore, we took an in vitro functional genomics approach to understand melanoma molecular pathways. METHODOLOGY/PRINCIPAL FINDINGS Af...
متن کاملAnalysis and Synthesis of Boolean Cell-cycle Gene Regulatory Networks
We provide a summary of Boolean network models for budding yeast cell-cycle including the Irons’ model. The model has 18 nodes and involves some auxiliary nodes which allow variability in time delays in the activation and degradation expression level of nodes. We also introduce a Boolean network exhibiting the cell-cycle behavior based on a family of cyclic codes, Projective Geometry codes, whi...
متن کاملTime dependent of epigenetic effect of disulfiram on tumor suppressor gene of RASSF1A in Hela cancer cell line
Introduction: Cervical cancer is the third most common tumor among women. Surgery, radiotherapy, and chemotherapy are common treatments, however high stage tumors have frequently poor prognosis. Nowadays, the epigenetic reversion introduced as an efficient strategy of treatment of cervical cancer. In the process, inhibitors of DNA methyltransferase (DNMT) induce re-expression of tumor suppresso...
متن کاملInvestigating lipopolymers based on polyethylenimine and nanoliposome for gene delivery to prostate cancer (PC3) cell line
Background: Non-viral Nano carriers such as liposomes and cationic polymers based on engineered properties are regarded in gene delivery field. Although these carriers do not have weaknesses of viral vectors, but they are less efficient than viruses and they still need to be improved as favorable gene delivery carriers. Amongst non-viral carriers, cationic liposomes have been proposed for clini...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Progress in Natural Science
سال: 2008
ISSN: 1002-0071
DOI: 10.1016/j.pnsc.2008.03.003